胃肠道间质瘤(gastrointestinal stromal tumors，GIST)是消化系统最常见的间叶性肿瘤。目前，GIST的治疗主要以手术切除为主，其后根据病理危险度分级不同辅助伊马替尼等靶向药物治疗。近年来，随着腹腔镜技术的不断发展和成熟，腹腔镜胃间质瘤切除术逐渐成为一种高效、微创的治疗方法，尤其是胃大弯侧间质瘤。腹腔镜胃间质瘤切除术虽然得到广泛应用，但是否适用于胃特殊部位的GIST和巨大的GIST仍存在争议。本文将结合笔者团队对腹腔镜胃间质瘤手术的探索及临床应用进行简要总结概述，为胃间质瘤的手术切除提供更优的治疗方法。

Gastrointestinal stromal tumors (GIST) is the most common mesenchymal tumors of the digestive system. At present, the main treatment of gastrointestinal stromal tumors is surgical resection, which is assisted by imatinib and other targeted drugs according to different pathological risk grades. In recent years, with the continuous development and maturity of laparoscopic technology, laparoscopic resection of gastric stromal tumors has gradually become an efficient and minimally invasive treatment, especially for large curved gastric stromal tumors. Although laparoscopic surgical resection of gastric stromal tumors has been widely used, it is still controversial whether laparoscopic surgery is suitable for special parts of the stomach GIST and giant GIST. In this study, combined with the author center′s exploration and clinical application of laparoscopic surgery in the treatment of gastric GIST, we will briefly summarize and summarize in order to choose a better way to treat GIST.