Laparoscopic subtotal colectomy NOSES surgery utilizing two different methods to extract the specimen combinatorially hasn′t been reported. We report one case of laparoscopic subtotal colectomy with complex NOESE surgery for a patient with familial adenomatous polyposis (FAP).

A FAP patient with rectal adenoma canceration was administrated in Gastrointestinal Surgery Center, Sichuan Cancer Hospital in Feb. 2019. Laparoscopic subtotal colectomy NOSES surgery was performed successfully, with colon specimen resection and extraction via rectum and rectal specimen resection via transanal eversion technique successively. The postoperative outcome was evaluated.

Operation time was 360 min and blood loss was 50 ml. In-hospital stay was 12 days and no surgical complications were noticed.

Laparoscopic subtotal colectomy with complex NOESE surgery is safe and feasible for patients with indications, which can better demonstrate the minimally invasive advantages of NOSES technology and may have a good prospect of clinical application.