To explore the safety and feasibility of laparoscopic radical trachelectomy in patients with uncommon subtype of cervical cancer who want to preserve reproductive function.

Retrospectively analyze the clinical datas of a case of invasive stratified mucin-producing carcinoma in the Department of Obstetrics and Gynecology, West China Second Hospital of Sichuan University in Dec. 2020. To show the steps of the surgery, and to summarize the technical points.

The surgery was successfully operated and the postoperative pathology showed invasive stratified mucin-producing carcinoma. After the surgery, the patient took mifepristone orally for 2.5 months and paclitaxel + cisplatin for chemotherapy 4 times. She recovered well. Regular review showed no abnormality, no menstrual irregularity, no menstrual blood obstruction, and normal ovarian function. The patient is currently preparing to conceive.

Laparoscopic radical trachelectomy for uncommon subtype of cervical cancer is safe and effective. It′s essential to remove sufficient range of paracervical tissue and ensure the incisal margin to be negative. The points and difficulties are that identifying the paracervial spaces, reducing bleeding and avoiding ureteral injury during the operation. The use of sentinel lymph node dissection and the preservation of the upper branch of uterine artery may make sense for reducing pelvic adhesion and preserving ovarian blood supply to the maximum extent.