Application of indocyanine green fluorescence imaging technology in thoracic surgery

doi:10.3877/cma.j.issn.1674-6899.2021.01.014

Abstract

Abstract:

Indocyanine green fluorescence imaging technology is a real-time imaging technology. It takes advantage of the fluorescent properties of indocyanine green, which can be excited by near-infrared light. The fluorescent signal it emits is collected by a special endoscopic system, and the signal is transmitted to the display so that the image can be seen in real time. It can look at specific targets during the operation, or show the blood perfusion of the tissue. In recent years, the physical properties of indocyanine green have been studied more and more deeply. Clinically, indocyanine green fluorescence imaging technology has been used in many aspects, such as vascular exploration, parenchymal organ perfusion development, soft tissue perfusion evaluation, lymphatic development, etc. This review focuses on the indocyanine green fluorescence imaging technology in thoracic surgery.

Key words: Indocyanine green, Minimally invasive surgical procedures, Lung surgery, Esophageal surgery

Junxi Hu, Liangliang Chen, Yusheng Shu. Application of indocyanine green fluorescence imaging technology in thoracic surgery[J]. Chinese Journal of Laparoscopic Surgery(Electronic Edition), 2021, 14(01): 61-64.

/ / Recommend

Add to citation manager EndNote|Ris|BibTeX

URL: https://zhqjwkzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.1674-6899.2021.01.014

https://zhqjwkzz.cma-cmc.com.cn/EN/Y2021/V14/I01/61

References 42

1	Schaafsma BE, Mieog JSD, Hutteman M, et al. The clinical use of indocyanine green as a near-infrared fluorescent contrast agent for image-guided oncologic surgery [J]. Journal of Surgical Oncology, 2011, 104(3): 323-332.
2	Gioux S, Choi HS, Frangioni JV. Image-guided surgery using invisible near-infrared light: fundamentals of clinical translation [J]. Molecular Imaging, 2010, 9(5): 237-255.
3	Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries [J]. CA: A Cancer Journal for Clinicians, 2018, 68(6): 394-424.
4	Okusanya Olugbenga T, Hess Nicholas R, Luketich James D, et al. Infrared intraoperative fluorescence imaging using indocyanine green in thoracic surgery[J]. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2018, 53(3): 512-518.
5	Boni L, David G, Mangano A, et al. Clinical applications of indocyanine green (ICG) enhanced fluorescence in laparoscopic surgery [J]. Surgical Endoscopy, 2015, 29(7): 2046-2055.
6	Desmettre T, Devoisselle JM, Mordon S. Fluorescence properties and metabolic features of indocyanine green (ICG) as related to angiography [J]. Surv Ophthalmol, 2000, 45(1): 15-27.
7	Alander JT, Kaartinen I, Laakso A, et al. A review of indocyanine green fluorescent imaging in surgery[J]. International Journal of Biomedical Imaging, 2012, 2012(1): 940585. DOI: 10.1155/2012/940585
8	Reinhart MB, Huntington CR, Blair LJ, et al. Indocyanine green [J]. Surgical Innovation, 2015, 23(2): 166-175.
9	Yannuzzi LA. Indocyanine green angiography: a perspective on use in the clinical setting [J]. American Journal of Ophthalmology, 2011, 151(5): 745-751.
10	Ogawa M, Kosaka N, Choyke PL, et al. In vivo molecular imaging of cancer with a quenching near-infrared fluorescent probe using conjugates of monoclonal antibodies and indocyanine green [J]. Cancer Research, 2009, 69(4): 1268-1272.
11	Moody ED, Viskari PJ, Colyer CL. Non-covalent labeling of human serum albumin with indocyanine green: a study by capillary electrophoresis with diode laser-induced fluorescence detection [J]. J Chromatogr B Biomed Sci Appl, 1999, 729(1): 55-64.
12	De Grand AM, Lomnes SJ, Lee DS, et al. Tissue-like phantoms for near-infrared fluorescence imaging system assessment and the training of surgeons [J]. J Biomed Opt, 2006, 11(1): 014007. DOI: 10.1117/1.2170579
13	Yousefi M, Ghaffari P, Nosrati R, et al. Prognostic and therapeutic significance of circulating tumor cells in patients with lung cancer [J]. Cell Oncol (Dordr), 2020, 43(1): 31-49.
14	Aberle DR, Demello S, Berg CD, et al. Results of the two incidence screenings in the national lung screening trial [J]. N Engl J Med, 2013, 369(10): 920-931.
15	Geraci TC, Ferrari-Light D, Kent A, et al. Technique, outcomes with navigational bronchoscopy using indocyanine green for robotic segmentectomy [J]. The Annals of Thoracic Surgery, 2019, 108(2): 363-369.
16	Anayama T, Qiu J, Chan H, et al. Localization of pulmonary nodules using navigation bronchoscope and a near-infrared fluorescence thoracoscope [J]. The Annals of Thoracic Surgery, 2015, 99(1): 224-230.
17	Bolton WD, Cochran T, Ben-Or S, et al. Electromagnetic navigational bronchoscopy reduces the time required for localization and resection of lung nodules [J]. Innovations (Phila), 2017, 12(5): 333-337.
18	陈亮，葛明建. 肺段切除术中段间平面显示方法的研究进展[J]. 中国肺癌杂志，2020, 23(9): 818-823.
19	Tane S, Nishio W, Nishioka Y, et al. Evaluation of the residual lung function after thoracoscopic segmentectomy compared with lobectomy [J]. The Annals of Thoracic Surgery, 2019, 108(5): 1543-1550.
20	张彤，马永富，石渊博，等. 荧光染色法与改良膨胀萎陷法判定段间平面在解剖性肺段切除术中的病例对照研究 [J/CD]. 中华腔镜外科杂志(电子版), 2019, 12(6): 356-360.
21	Misaki N, Chang SS, Gotoh M, et al. A novel method for determining adjacent lung segments with infrared thoracoscopy [J]. The Journal of Thoracic and Cardiovascular Surgery, 2009, 138(3): 613-618.
22	Matsuura Y, Mun M, Ichinose J, et al. Recent fluorescence-based optical imaging for video-assisted thoracoscopic surgery segmentectomy [J]. Ann Transl Med, 2019, 7(2): 32-32.
23	Landsman ML, Kwant G, Mook GA, et al. Light-absorbing properties, stability, and spectral stabilization of indocyanine green [J]. J Appl Physiol, 1976, 40(4): 575-583.
24	Chen R, Ma Y, Li C, et al. A pilot study of pulmonary segmentectomy with indocyanine green near-infrared angiography[J]. Surgical Innovation, 2019, 26(3): 337-343.
25	Mehta M, Patel YS, Yasufuku K, et al. Near-infrared mapping with indocyanine green is associated with an increase in oncological margin length in minimally invasive segmentectomy [J]. The Journal of Thoracic and Cardiovascular Surgery, 2019, 157(5): 2029-2035.
26	Veronesi U, Paganelli G, Galimberti V, et al. Sentinel-node biopsy to avoid axillary dissection in breast cancer with clinically negative lymph-nodes[J]. Lancet, 1997, 349(9069): 1864-1867.
27	Albertini JJ, Cruse CW, Rapaport D, et al. Intraoperative radio-lympho-scintigraphy improves sentinel lymph node identification for patients with melanoma [J]. Ann Surg, 1996, 223(2): 217-224.
28	Thompson JF, Mccarthy WH, Bosch CM, et al. Sentinel lymph node status as an indicator of the presence of metastatic melanoma in regional lymph nodes [J]. Melanoma Res, 1995, 5(4): 255-260.
29	Little AG, Dehoyos A, Kirgan DM, et al. Intraoperative lymphatic mapping for non-small cell lung cancer: the sentinel node technique[J]. Journal of Thoracic & Cardiovascular Surgery, 1999, 117(2): 220-220.
30	Tajima Y, Murakami M, Yamazaki K, et al. Sentinel node mapping guided by indocyanine green fluorescence imaging during laparoscopic surgery in gastric cancer [J]. Annals of Surgical Oncology, 2010, 17(7): 1787-1793.
31	Gilmore DM, Khullar OV, Jaklitsch MT, et al. Identification of metastatic nodal disease in a phase 1 dose-escalation trial of intraoperative sentinel lymph node mapping in non-small cell lung cancer using near-infrared imaging[J]. The Journal of Thoracic and Cardiovascular Surgery, 2013, 146(3): 562-570.
32	Darling GE. Commentary on "finding the true " no " cohort: technical aspects of near-infrared sentinel lymph node mapping in non-small cell lung cancer" [J]. Ann Surg, 2020, 272(4): 589-589.
33	Jemal A, Bray F, Center MM, et al. Global cancer statistics [J]. CA: A Cancer Journal for Clinicians, 2011, 61(2): 69-90.
34	Nagpal K, Ahmed K, Vats A, et al. Is minimally invasive surgery beneficial in the management of esophageal cancer. a meta-analysis [J]. Surgical Endoscopy, 2010, 24(7): 1621-1629.
35	Rino Y, Yukawa N, Sato T, et al. Visualization of blood supply route to the reconstructed stomach by indocyanine green fluorescence imaging during esophagectomy[J]. BMC Med Imaging, 2014, 14(1): 8-8.
36	Ohi M, Toiyama Y, Mohri Y, et al. Prevalence of anastomotic leak and the impact of indocyanine green fluorescein imaging for evaluating blood flow in the gastric conduit following esophageal cancer surgery[J]. Esophagus, 2017, 14(4): 351-359.
37	Zehetner J, Demeester SR, Alicuben ET, et al. Intraoperative assessment of perfusion of the gastric graft and correlation with anastomotic leaks after esophagectomy [J]. Annals of Surgery, 2015, 262(1): 74-78.
38	Vecchiato M, Martino A, Sponza M, et al. Thoracic duct identification with indocyanine green fluorescence during minimally invasive esophagectomy with patient in prone position [J]. Dis Esophagus, 2020.DOI: 10.1093/dote/doaa030
39	Brinkmann S, Schroeder W, Junggeburth K, et al. Incidence and management of chylothorax after Ivor Lewis esophagectomy for cancer of the esophagus [J]. J Thorac Cardiovasc Surg, 2016, 151(5): 1398-1404.
40	Reisenauer JS, Puig CA, Reisenauer CJ, et al. Treatment of postsurgical chylothorax [J]. Ann Thorac Surg, 2018, 105(1): 254-262.
41	Petri R, Zuccolo M, Brizzolari M, et al. Minimally invasive esophagectomy: thoracoscopic esophageal mobilization for esophageal cancer with the patient in prone position [J]. Surg Endosc, 2012, 26(4): 1102-1107.
42	Mihara M, Hara H, Shibasaki J, et al. Indocyanine green lymphography and lymphaticovenous anastomosis for generalized lymphatic dysplasia with pleural effusion and ascites in neonates [J]. Annals of Vascular Surgery, 2015, 29(6): 1111-122.

[1]	Chen Wang, Haoran Yu, Huihui Guo, Xianbo Shang, Sai Ma, Xingyu You, Dechao Cai, Xiao Ma, Haotian Zhang, Ashuai Bian, Wendan Cheng. Research progress of minimally invasive total knee arthroplasty [J]. Chinese Journal of Joint Surgery(Electronic Edition), 2021, 15(03): 339-344.
[2]	Kun Chen, Qi Li. Advances of minimally invasive anterolateral approach in total hip arthroplasty [J]. Chinese Journal of Joint Surgery(Electronic Edition), 2020, 14(05): 608-611.
[3]	Zhengran Mo, Ganxi Zhou, Jingwang Wang, Chunrong Guo. Effects of minimally invasive locking compression plate on joint function and complication in distal tibiofibular fracture [J]. Chinese Journal of Joint Surgery(Electronic Edition), 2020, 14(03): 334-338.
[4]	Weifeng Lan, Zhijian Chen, Hanyin Hong, Jianwei Chen, Xinghua Huang, Xiaobin Chi, Yongbiao Chen. Application of indocyanine green in laparoscopic hepatectomy [J]. Chinese Archives of General Surgery(Electronic Edition), 2021, 15(04): 309-312.
[5]	Weidong Tang, Jiewen Deng, Chao Jiang, Xiulin Yang, Xia Chen. Anatomical observation and three-dimensional reconstruction combined with ICG imaging in 86 cases of hilar cholangiocarcinoma [J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2021, 15(04): 392-395.
[6]	Xiaofeng Lu, Song Liu, Shichao Ai, Xuefeng Xia, Xiaofei Shen, Peng Song, Xing Kang, Liming Zheng, Meng Wang, Wenxian Guan. Comparative study of carbon nanoparticles and indocyanine green-guided lymphadenectomy during laparoscopic radical gastrectomy [J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2021, 15(02): 146-149.
[7]	Shangheng Shi, Jianhong Wang, Shuxian Wang, Lijiang Wang, Feng Wang, Ge Guan, Yunjin Zang. Preliminary study on the clinical value of the combined application of indocyanine green test and two-dimensional shear wave elastography in the assessment of donor liver quality [J]. Chinese Journal of Transplantation(Electronic Edition), 2020, 14(03): 154-158.
[8]	Bo Wu, Caoyang Hu, Pengliang Shen, Nan Yin, Tao Bai, Yuan Shao, Dongwen Wang. Preliminary clinical experiences of fluorescence imaging in Robot-assisted radical prostatectomy [J]. Chinese Journal of Endourology(Electronic Edition), 2020, 14(06): 414-419.
[9]	Chenggang Li, Zhiming Zhao, Minggen Hu, Xianglong Tan, Xuan Zhang, Zhipeng Zhou, Nan Jiang, Yuze Jia. Application of indocyanine green in robotic resection of liver FNH [J]. Chinese Journal of Laparoscopic Surgery(Electronic Edition), 2021, 14(01): 15-18.
[10]	Ao Yu, Zichen Jiao, Tao Wang. Application of early removal of chest tube after video-assisted thoracoscopic lung surgery [J]. Chinese Journal of Laparoscopic Surgery(Electronic Edition), 2020, 13(06): 347-351.
[11]	Zhen Li, Mingxia Ye, Wen Yang, Wensheng Fan, Li′an Li, Yuanguang Meng. Robotic deep infiltrating endometriosis surgery guided by near-infrared fluorescence imaging with indocyanine green: a case report and literature review [J]. Chinese Journal of Laparoscopic Surgery(Electronic Edition), 2020, 13(04): 247-249.
[12]	Xiuping Zhang, Shuai Xu, Zhiming Zhao, Rong Liu. Application of ICG "four-zone three-phase" fluorescence imaging in robot-assisted anatomical hepatectomy [J]. Chinese Journal of Hepatic Surgery(Electronic Edition), 2021, 10(02): 191-196.
[13]	Rui Du, Jiajie Zhou, Feng Wang, Dongliang Li, Guifan Tong, Xu Ding, Qi Zhang, Wei Wang, Liuhua Wang, Dong Tang, Daorong Wang. Indocyanine green-fluorescence imaging-assisted laparoscopic individualized lateral lymph node dissection strategy in the treatment for low-grade rectal cancer: Five cases report [J]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2021, 10(02): 211-215.
[14]	Lihua Chen, Yong Xia, Kai Sun, Wenjin Chen, Hongtian Zhang, Ruxiang Xu. Research progress of the application of intraoperative tumor fluorescent agents [J]. Chinese Journal of Brain Diseases and Rehabilitation(Electronic Edition), 2021, 11(02): 109-115.
[15]	Yixin Sun, Songping Cui, Hui Li, Yi Liu, Lihui Ke. Efficacy and safety of the anticoagulation prophylaxis on perioperative venous thromboembolism in thoracic surgery based on propensity score matching [J]. Chinese Journal of Thoracic Surgery(Electronic Edition), 2021, 08(01): 21-35.

Please choose a citation manager

Content to export