初步探讨全腹腔镜胃部分离断胃空肠转流术(total laparoscopic stomach-partitioning gastrojejunostomy，TLSPGJ)治疗上消化道克罗恩病出口梗阻的技术可行性、安全性及短期临床效果。

回顾性分析2024年1月至2025年8月间上海交通大学医学院附属瑞金医院普外科由同一手术团队诊治的6例上消化道克罗恩病出口梗阻患者的临床资料。所有患者均接受TLSPGJ。记录并分析每个病例的手术时间、术中出血量、术后胃肠功能恢复时间，术后住院天数，围术期并发症发生率及术后短期生活质量改善情况。

6例手术均在腹腔镜下顺利完成，无中转开腹。平均手术时间为90.8±22.0 min，平均术中出血量为28.3±13.3 ml。术后胃肠功能恢复时间为2.0±0.9 d，术后平均住院时间为6.8±1.7 d。术后出现1例Clavien-Dindo I级并发症(切口脂肪液化)，经换药后愈合，无吻合口漏、腹腔感染等严重并发症发生。术后3个月所有患者梗阻症状均解除，营养状况、生活质量得到显著改善，随访期间无疾病复发及进展。

本研究结果表明，全腹腔镜胃部分离断胃空肠转流术治疗上消化道克罗恩病出口梗阻在技术上是安全可行的，具有创伤小、恢复快的优点，其近期临床效果令人满意。该术式可作为经严格选择患者的一种微创治疗选择，其长期疗效有待更大样本量和更长随访时间的研究进一步验证。

To preliminarily investigate the technical feasibility, safety, and short-term clinical outcomes of total laparoscopic stomach-partitioning gastrojejunostomy (TLSPGJ) for treating outlet obstruction in upper gastrointestinal Crohn′s disease.

Clinical data were retrospectively analyzed for six patients with upper gastrointestinal Crohn′s disease outlet obstruction treated by the same surgical team between Jan. 2024 and Aug. 2025. All patients underwent TLSPGJ. The following parameters were recorded and analyzed for each case: operative time, intraoperative blood loss, time to postoperative gastrointestinal function recovery, postoperative hospital stay, perioperative complication rate, and short-term postoperative quality of life improvement.

All six procedures were successfully completed laparoscopically without conversion to open surgery. Mean operative time was 90.8±22.0 minutes, with mean intraoperative blood loss of 28.3±13.3 ml. Mean time to gastrointestinal recovery was 2.0±0.9 days, and mean postoperative hospital stay was 6.8±1.7 days. One Clavien-Dindo Grade I complication (incisional fat liquefaction) occurred postoperatively, resolving after wound dressing changes. No severe complications such as anastomotic leakage or intra-abdominal infection were observed. All patients experienced resolution of obstructive symptoms at three months postoperatively, with marked improvement in nutritional status and quality of life. No disease recurrence or progression was noted during follow-up period.

These findings demonstrate that TLSPGJ is technically safe and feasible for treating outlet obstruction in upper gastrointestinal Crohn′s disease. This approach offers advantages of minimal trauma and rapid recovery, with satisfactory short-term clinical outcomes. It may serve as a minimally invasive treatment option for carefully selected patients, though long-term efficacy requires further validation through larger sample sizes and extended follow-up periods.