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中华腔镜外科杂志(电子版) ›› 2021, Vol. 14 ›› Issue (01): 44 -48. doi: 10.3877/cma.j.issn.1674-6899.2021.01.010

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机器人直视下切除低位直肠癌下切缘行保肛手术
柳欣欣 1, 阚明韵 1, 江志伟 1 , ( ), 王立文 1, 李玉萍 1, 戴洪山 1, 刘江 1   
  1. 1. 210029 南京中医药大学附属医院 江苏省中医院普通外科
  • 收稿日期:2020-12-23 出版日期:2021-02-28
  • 通信作者: 江志伟

The technique of cutting off the lower margin under robot′s direct vision in the abdominal cavity for low rectal cancer radical resection and anal preserving surgery

Xinxin Liu 1, Mingyun Kan 1, Zhiwei Jiang 1 , ( ), Liwen Wang 1, Yuping Li 1, Hongshan Dai 1, Jiang Liu 1   

  1. 1. Affiliated Hospital of Nanjing University of Chinese Medicine, General Surgery, Nanjing 210029, China
  • Received:2020-12-23 Published:2021-02-28
  • Corresponding author: Zhiwei Jiang
目的

低位直肠癌机器人腹腔内直视下切断下切缘行全直肠系膜切除术,探索该术式的疗效及优势。

方法

回顾2020年5~12月江苏省中医院采用机器人腹腔内直视下低位直肠癌根治术保肛治疗3例患者的临床资料,平均年龄65.7岁。术前患者全部确诊为直肠癌,肿瘤下缘距肛缘2.0~3.5 cm,均未累及肛管。

结果

3例手术均顺利完成,术中未中转开腹及增加操作通道。手术时间平均约290 min,术中出血量平均约80 ml。术后2 h,患者麻醉清醒后即可进少量流食。均在术后1 d拔除导尿管,自行排尿顺畅,无尿潴留表现。术后肛门排气时间平均约1.8 d,术后住院时间平均4.8 d。标本下切缘及中低位直肠癌环周切缘均为阴性,下切缘距肿瘤距离平均1.8 cm。术后3个月肛门指检及肠镜检查吻合口愈合良好。所有患者按计划均顺利完成造口还纳。术后患者肛门控便功能良好,无术后局部吻合口周围感染、吻合口出血、吻合口瘘及狭窄等并发症。

结论

低位直肠癌根治行保肛手术,在机器人腹腔内直视下切断下切缘技术行之有效,是低位直肠癌根治保肛手术的一种有益尝试,临床结果良好,值得进一步研究应用。

Objective

To explore the curative effect and advantages of the new surgical procedure for low rectal cancer by robotic intraabdominal incision of the lower margin and total mesorectal excision(TME).

Methods

3 patients, with an average age of 65.7 years, were treated with robotic laparoscopic radical anal preservation for low rectal cancer in Jiangsu Hospital of Traditional Chinese Medicine from May to Dec. 2020. The clinical data of these patients were reviewed. All the patients were diagnosed with rectal cancer preoperatively, and the lower margin of the tumor was 2.0-3.5 cm from the anal margin, and no anal canal was involved.

Results

The operation of 3 patients was completed successfully, and there was no transfer to laparotomy or increase of operation channel. The average operation time was about 290 min, and the average intraoperative bleeding was about 80 ml. Two hours after the operation, a small amount of fluid diet can be entered after anesthesia awake. All the patients had their catheters removed on the first day after surgery and urinated smoothly without urinary retention. The average postoperative anal exhaust time was about 1.8 days, and the average postoperative hospital stay was 4.8 days. The lower margin and CRM margin of the specimen pathological examination were negative, and the average distance from the lower margin to the tumor was 1.8 cm. The anastomosis healed well by digital anal examination and colonoscopy 3 months after operation. All patients successfully completed stoma closed as planned. The patients had good anal defecation function after operation, and no postoperative complications such as local infection around the anastomotic site, anastomotic bleeding, anastomotic fistula and stenosis occurred.

Conclusions

The technique of cutting off the lower margin under robot′s direct vision in the abdominal cavity is effective for the radical resection of low rectal cancer with anal preserving, which is a beneficial attempt for the operation of low rectal cancer. The clinical results are good, and it is worthy of further study and application.

图1 术中戳卡分布及达芬奇机器人手术系统机械臂分布
图2 戳卡分布示意及达芬奇机器人手术系统操作布局
图3 机器人手术中操作过程
图4 经肛荷包管型吻合器重建
图5 术后复查肠镜见吻合口愈合良好
1
Ferlay J, Soerjomataram I, Dikshit R, et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012[J]. International Journal of Cancer, 2015, 136(5): 359-386.
2
Lindsey, Torre A, MSPH, et al. Global cancer statistics, 2012[J]. Ca A Cancer Journal for Clinicians, 2015, 65(2): 87-108.
3
陈功. 2017年美国临床肿瘤学会年会结直肠癌研究进展解析[J]. 中华消化外科杂志,2017,16(16): 668-673.
4
郁宝铭. 对直肠癌划分高位、中位、低位和超低位临床意义的再认识[J]. 中华胃肠外科杂志,2011,14(10):821-822.
5
王序杰,周岩冰. 机器人直肠癌手术现状[J]. 临床外科杂志,2020, 28(5):489-492.
6
Heald RJ, Husband EM, Ryall RDH. The mesorectum in rectal cancer surgery--the clue to pelvic recurrence[J]. Br J Surg, 2010, 69(10): 613-616.
7
杜晓辉. 腹腔镜和达芬奇机器人系统在胃肠外科中的应用[J].上海医药,2014, 35(23): 4-7,16.
8
石文华. 用腹腔镜结直肠癌根治术对老年结直肠癌患者进行治疗的效果分析[J]. 当代医药论丛,2017, 15(5): 27-28.
9
刘洪昌,李川,张帆,等 达芬奇机器人低位直肠癌经括约肌间切除术临床疗效分析[J]. 中华胃肠外科杂志,2019, 22(12):1137-1143.
10
Ballantyne GH. Telerobotic gastrointestinal surgery: phase 2-safety and efficacy[J]. Surgical Endoscopy, 2007, 21(7): 1054-1062.
11
池畔,陈致奋. 机器人与腹腔镜全直肠系膜切除术的比较[J].中华胃肠外科杂志,2017, 20(6): 610-613.
12
许剑民,许平平,冯青阳. 机器人在直肠癌治疗中的应用[J].腹部外科,2020, 33(2): 153-155.
13
卓凡. 达芬奇机器人与腹腔镜直肠癌前切除术的回顾性分析[D].南昌大学,2019.
14
Speicher PJ, Englum BR, Ganapathi AM, et al. Robotic low anterior resection for rectal cancer: a national perspective on short-term oncologic outcomes[J]. Annals of surgery, 2015, 262(6): 1040-1045.
15
Baek JH, Mckenzie S, Garcia-aguilar J, et al. Oncologic outcomes of robotic-assisted total mesorectal excision for the treatment of rectal cancer[J]. Annals of surgery, 2010, 251(5): 882-886.
16
中华人民共和国卫生和计划生育委员会医政医管局,中华医学会肿瘤学分会. 中国结直肠癌诊疗规范(2017年版) [J]. 中华外科杂志,2018, 56(4): 241-258.
17
Engstrom PF, Arnoletti JP, Benson AB, et al. NCCN clinical practice guidelines in oncology: rectal cancer [J]. J Natl Compr Canc Netw, 2009, 7(8): 838-881.
18
Fukunaga M, Kidokoro A, Iba T, et al. Laparoscopy-assisted low anterior resection with a prolapsing technique for low rectal cancer [J]. Surg Today, 2005, 35(7): 598-602.
19
Wexner SD. Restorative proctectomy with colon pouch-anal anastomosis by laparoscopic transanal pull-through: an available option for low rectal cancer[J]. Surg Endosc, 2007, 21(9): 1679-1679.
20
Collard M, Jérémie H. Lefevre. ultimate functional preservation with intersphincteric resection for rectal cancer[J]. Frontiers in Oncology, 2020. DOI: 10.3389/fonc.2020.00297
21
Penna M, Hompes R, Arnold S, et al. Transanal total mesorectal excision: international registry results of the first 720 cases [J]. Ann Surg, 2017, 266(1): 111-117.
22
Larsen SG, Pfeffer F, Korner H, et al. Norwegian moratorium on transanal total mesorectal excision [J]. Br J Surg, 2019, 106(9): 1120-1121.
23
Motson RW, Whiteford MH, Hompes R, et al. Current status of trans-anal total mesorectal excision (TaTME) following the second international consensus conference [J]. Colorectal Dis, 2016, 18(1): 13-18.
24
Chi P, Chen Z, Lu X. Transanal total mesorectal excision: can it achieve the standard of TME[J]. Ann Surg, 2017, 266(6): 87-88.
25
Colombo PE, Bertrand MM, Alline M, et al. Robotic versus laparoscopic total mesorectal excision (TME) for sphincter-saving surgery: is there any difference in the transanal tme rectal approach: a single-center series of 120 consecutive patients [J]. Ann Surg Oncol, 2016, 23(5): 1594-1600.
26
Xu Pingping, Xu Jianmin. Application of robotic surgical system in sphincter-preserving surgery for low rectal cancer[J]. Zhong hua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery, 2017, 20(6): 606-609.
27
Kim JC, Lee JL, Bong JW, et al. Oncological and anorectal functional outcomes of robot-assisted intersphincteric resection in lower rectal cancer, particularly the extent of sphincter resection and sphincter saving [J]. Surg Endosc, 2020, 34(5): 2082-2094.
28
刘洪昌,李川,张帆,等. 达芬奇机器人低位直肠癌经括约肌间切除术临床疗效分析[J]. 中华胃肠外科杂志,2019, 22(12): 1137-1143.
29
刘洪昌,王晓松,高林丰,等. 达芬奇机器人直肠癌经括约肌间切除术超低位吻合相关并发症分析[J]. 第三军医大学学报,2019, 41(18): 1796-8101.
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