探讨应用混合现实技术辅助肺小结节精准定位的可行性。

选取解放军总医院第一医学中心胸外科的肺部小结节患者1例，术前检查完善，无绝对手术禁忌，拟行胸腔镜肺楔形切除术。术前利用患者平卧位胸部CT对患者体表及靶病变进行三维重建，拟定辅助线，使用hookwire定位针对靶病变进行穿刺定位，利用术中CT进一步验证定位的准确性，进而对病变进行楔形切除。

病变定位准确，患者术后4 d顺利出院。

混合现实技术辅助下肺小结节精准定位切除病例1例，定位过程顺利，定位准确，有望开创胸外科肺小结节定位中新篇章，该技术的进一步探索和应用将为胸外科手术带来更多的发展可能和进步前景。

To explore the feasibility of using mixed reality technique to assist the accurate localization of pulmonary nodules.

A patient with a small pulmonary nodule in Department of Thoracic Surgery, Chinese PLA General Hospital was selected and underwent thoracoscopic pulmonary wedge resection with perfect preoperative examination and no absolute surgical contraindication. The chest CT in supine position was used to reconstruct the body surface and the target lesion before operation. The auxiliary line was drawn up and the hookwire localization was used to localize the target lesion. At last, the accuracy of localization was further verified by CT in the OR. Then the lesion was resected completely.

The location of the lesion was accurate and the patient was discharged from hospital successfully 4 days after the surgery.

This paper reports a case of accurate localization of a small pulmonary nodule assisted by mixed reality technique. The localization process was smooth and accurate, which is expected to open a new chapter in the localization of small pulmonary nodules in thoracic surgery. The further exploration and application of this technology will bring more development and prospect for thoracic surgery.