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中华腔镜外科杂志(电子版) ›› 2016, Vol. 09 ›› Issue (02): 100 -105. doi: 10.3877/cma.j.issn.1674-6899.2016.02.013

所属专题: 经典病例 文献资源库

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腹腔镜、内镜在Mirizzi综合征I型患者中的应用(附11例报告)
李广阔 1 , ( ), 李鑫 1, 冯犁 1, 李水芹 1, 李莉 2, 张洁 1, 杨海霞 1   
  1. 1. 610072 成都中医药大学附属医院肝胆外科
    2. 610072 成都中医药大学附属医院放射科
  • 收稿日期:2016-02-01 出版日期:2016-04-30
  • 通信作者: 李广阔
  • 基金资助:
    成都市科技局"科技惠民计划项目"(2013)

Application of laparoscopic and endoscopic procedures in patients with Csendes I Mirizzi Syndrome: report of 11 cases

Guangkuo Li 1 , ( ), Xin Li 1, Li Feng 1, Shuiqin Li 1, Li Li 2, Jie Zhang 1, Haixia Yang 1   

  1. 1. Department of Hepatobiliary Surgery, Teaching Hospital of Chengdu University of T. C.M, Chengdu 610072, China
    2. Department of Radiology, Teaching Hospital of Chengdu University of T. C.M, Chengdu 610072, China
  • Received:2016-02-01 Published:2016-04-30
  • Corresponding author: Guangkuo Li
  • About author:
    Corresponding author: Li Guangkuo, Email:
目的

探讨腹腔镜、内镜等微创技术在Mirizzi综合征(MS)Csendes I型患者"个体化诊疗"中的应用。

方法

纳入成都中医药大学附属医院2013年11月至2015年12月施行腹腔镜胆囊切除术(LC)的患者900余例,进行回顾性分析。对病史中有黄疸、生化检查提示血胆红素升高和超声检查提示胆囊结石且肝总管或胆总管直径大于0.8 cm的患者,术前全部进行MRCP及ERCP,发现符合MS的患者24例,占同期LC患者的2.7%(24/900)。将其中Csendes I型11例纳入本研究,分析其临床特征及诊治特点。

结果

11例Csendes I型患者中,Csendes Ia型6例,3例合并继发性胆总管结石,其中2例发生急性胆管炎;Csendes Ib型5例,2例合并继发性胆总管结石,其中1例发生急性胆管炎。所有患者行ERCP时一并清除胆总管内取石,留置ENBD管引流胆道,以改善肝功能。11例患者在ERCP后3~7 d成功施行了LC,仅1例Ia型患者胆囊管结石嵌顿,于LC中中转开腹,经胆囊管行胆道镜下的碎石取石。

结论

怀疑MS的患者应行MRCP和ERCP,采用Csendes(1989,2008)标准进行准确分型,以便对肝外胆道的受损程度进行评估、合理抉择治疗策略。Csendes Ia型和Ib型患者均可行LC,但术中应利用胆道镜进行胆囊管探查及碎石取石,尽可能避免胆道探查,以防止医源性胆管狭窄。

Objective

To evaluate laparoscopic and endoscopic procedures in individualized diagnosis and therapy of Mirizzi Syndrome(Csendes Type I).

Methods

Retrospective study was carried out in 900 patients undergoing laparoscopic cholecystectomy(LC) from Nov. 2013 to Dec. 2015. Magnetic cholangiopancreatography(MRCP) and Endoscopic retrograde cholangiopancreatography(ERCP) were done in 24 cases(24/900, 2.7%) for the following reasons: cholecystitis with history of jaundice; abnormal bilirubin showed by serum chemical study; gallbladder stone(s) and enlargement(>0.8 cm) of intrahepatic or extrahepatic biliary tract by ultrasound. According the criteria of MS, 24 cases were diagnosed and 11 of them were type 1 MS(Csendes classification), whose clinical data were analyzed retrospectively.

Results

All of the 11 cases underwent LC 3-7 days after ERCP, whose stones were removed and bile duct drained by ENBD. Only one case was converted laparotomy because of incarcerated cystic duct stones, which were be shattered and removed under choledochoscopy. Among the 11 cases, 6 were Csendes Ia(3 with secondary common bile duct stone, 2 with acute cholangitis) and 5 were Csendes Ib(2 with secondary common bile duct stone, 1 with acute cholangitis).

Conclusions

Suspected patients with MS should be performed with MRCP and ERCP and classified with Csendes classification(1989, 2008) for evaluating damage of extrahepatic biliary tract and choice of therapeutic strategy. Csendes Ia and Ib can be operated under laparoscopy, but stones in cystic duct should be explored and extracted after lithotripsy under choledochoscopy. Free of biliary tract exploration would be beneficial to avoid iatrogenic biliary tract stricture.

表1 Mirizzi综合征中11例Csendes I型患者的情况
序号 性别 年龄(岁) 病程(年) TBIL/DBIL(mmol/L) 是否肝内胆管扩张 是否胆总管结石/扩张 内镜诊疗 诊断 MS分型 手术方案 治疗结果 术后住院时间(d)
1 36 1.5 310/227 是/是 ERCP+EST+取石+ENBD 梗阻性黄疸,继发性胆总管结石,急性胆管炎;胆囊结石、慢性胆囊炎 Ia A 痊愈 4
2 73 20.0 170/110 是/是 ERCP+EST+取石+ENBD 梗阻性黄疸,继发性胆总管结石,急性胆管炎;胆囊结石、慢性胆囊炎 Ia A 痊愈 3
3 46 2.0 55/34 是/是 ERCP+EST+取石+ENBD 梗阻性黄疸,继发性胆总管结石;胆囊结石、慢性胆囊炎 Ia A 痊愈 5
4 71 4.0 92/76 是/是 ERCP+EST+取石+ENBD 梗阻性黄疸,继发性胆总管结石,急性胆管炎;胆囊结石、慢性胆囊炎 Ib B 痊愈 7
5 66 7.0 77/51 是/是 ERCP+EST+取石+ENBD 梗阻性黄疸,继发性胆总管结石;胆囊结石、慢性胆囊炎 Ib B 痊愈 4
6 67 3.5 116/78 否/否 ERCP+ENBD 梗阻性黄疸,胆囊结石、慢性胆囊炎 Ib B 痊愈 4
7 78 2.5 134/91 否/否 ERCP+ENBD 梗阻性黄疸,胆囊结石、慢性胆囊炎 Ib B 痊愈 4
8 62 12.0 243/160 否/否 ERCP+ENBD 梗阻性黄疸,胆囊结石、慢性胆囊炎 Ia A 痊愈 3
9 56 10.0 76/51 否/否 ERCP+ENBD 梗阻性黄疸,胆囊结石、慢性胆囊炎 Ia A 痊愈 4
10 35 5.0 90/65 否/否 ERCP+ENBD 梗阻性黄疸,胆囊结石、慢性胆囊炎 Ib B 痊愈 4
11 47 8.5 87/58 否/否 ERCP+ENBD 梗阻性黄疸,胆囊结石、慢性胆囊炎 Ia A 痊愈 4
图1 Csendes Ia型患者的影像特征
图2 Csendes Ib型患者的影像特征
图3 Csendes Ia型与Ib型的个体化手术策略示意
图4 腹腔镜下胆囊管探查及缝合
图5 Csendes分型示意 (1989,2008)
1
Johnson LW, Sehon JK, Chapman LW, et al. Mirizzi’s syndrome: experience from a multi-institutional review[J]. Am Surg, 2001, 67(1): 11-14.
2
Abou-Saif A, Al-Kawas FH. Complications of gallstone disease: Mirizzi syndrome, cholecystocholedochal fistula and gallstone ilues[J]. Am J Gastroenterol, 2002, 97(2): 249-254.
3
Contini S, Dalla VR, Zinicola R, et al. Undiagnosed Mirizzi′s syndrome: a word of caution for laparoscopic surgeons-a report of three cases and review of the literature[J]. J Laparoendosc Adv Surg Tech A, 1999, 9(2): 197-203.
4
李际辉,郑成竹,仇明,等. 54例Mirizzi综合征的腹腔镜治疗[J]. 中华普通外科杂志,2001, 16(6): 334-335.
5
Becker CD, Grossholz M, Becker M, et al. Cholelithiasis and bile duct stenosis diagnostic accuracy of mr cholagiopancreatography[J]. Radiology, 1997, 205(2): 523-530.
6
Marinis A, Kalaitzis I, Basioukas P, et al. Vascular complications of large gallstones: proposal of α first classification[J]. Hellēnikē Cheirourgikē Acta Chirurgica Hellenica, 2013, 84(5): 318-322.
7
Beltran MA, Csendes ACruces KS. The relationship of Mirizzi syndrome and cholecystoenteric fistula: validation of a modified classification[J]. World Journal of Surgery, 2008, 32(10): 2244-2245.
8
何晓东,赵玉沛,高鹏,等. Mirizzi综合征的外科诊治体会[J]. 中华肝胆外科杂志,2001, 7(5): 278-279.
9
Hazzan D, Golijanin D, Reissman P, et al. Combined endoscopic and surgical management of Mirizzi syndrome[J]. Surgical Endoscopy, 1999, 13(6): 618-620.
10
Abou-Saif A, Al-Kawas FH. Complications of gallstone disease: Mirizzi syndrome, cholecystocholedochal fistula, and gallstone ileus[J]. American Journal of Gastroenterology, 2002, 97(2): 249-254.
11
Targarona EM, Andrade E , Balagué C , et al. Mirizzi′s syndrome. diagnostic and therapeutic controversies in the laparoscopic era[J]. Surgical Endoscopy, 1997, 11(8): 842-845.
12
Kok KYY, Goh PYM, Ngoi SS. Management of Mirizzi′s syndrome in the laparoscopic era[J]. Surgical Endoscopy, 1998, 12(10): 1242-1244.
13
Corts MR, Vasquez AG. Frequency of the Mirizzi syndrome in a teaching hospital[J]. Cir Gen, 2003, 25(3): 334-337.
14
Beltran MA, Csendes AC, ruces KS. The relationship of Mirizzi syndrome and cholecystoenteric fistula: validation of a modified classification[J]. World Journal of Surgery, 2008, 32(10): 2244-2245.
15
李为民,萧荫祺,刘浩润,等. Mirizzi综合征与腹腔镜胆囊切除术中的胆管损伤[J]. 中华肝胆外科杂志,2004, 10(2): 140-141.
16
Antoniou SA, Antoniou GA, Makridis C. Laparoscopic treatment of Mirizzi syndrome: a systematic review[J]. Surgical Endoscopy, 2010, 24(1): 33-39.
17
周旭,易继林,郭悦青,等. Mirizzi综合征的手术治疗(附3例报告)[J]. 中国普通外科杂志,2002, 11(2): 71-73.
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