To preliminarily investigate the technical feasibility, safety, and short-term clinical outcomes of total laparoscopic stomach-partitioning gastrojejunostomy (TLSPGJ) for treating outlet obstruction in upper gastrointestinal Crohn′s disease.

Clinical data were retrospectively analyzed for six patients with upper gastrointestinal Crohn′s disease outlet obstruction treated by the same surgical team between Jan. 2024 and Aug. 2025. All patients underwent TLSPGJ. The following parameters were recorded and analyzed for each case: operative time, intraoperative blood loss, time to postoperative gastrointestinal function recovery, postoperative hospital stay, perioperative complication rate, and short-term postoperative quality of life improvement.

All six procedures were successfully completed laparoscopically without conversion to open surgery. Mean operative time was 90.8±22.0 minutes, with mean intraoperative blood loss of 28.3±13.3 ml. Mean time to gastrointestinal recovery was 2.0±0.9 days, and mean postoperative hospital stay was 6.8±1.7 days. One Clavien-Dindo Grade I complication (incisional fat liquefaction) occurred postoperatively, resolving after wound dressing changes. No severe complications such as anastomotic leakage or intra-abdominal infection were observed. All patients experienced resolution of obstructive symptoms at three months postoperatively, with marked improvement in nutritional status and quality of life. No disease recurrence or progression was noted during follow-up period.

These findings demonstrate that TLSPGJ is technically safe and feasible for treating outlet obstruction in upper gastrointestinal Crohn′s disease. This approach offers advantages of minimal trauma and rapid recovery, with satisfactory short-term clinical outcomes. It may serve as a minimally invasive treatment option for carefully selected patients, though long-term efficacy requires further validation through larger sample sizes and extended follow-up periods.