Safety and feasibility of single port laparoscopic hepatectomy for hepatocellular carcinoma: a retrospective study

doi:10.3877/cma.j.issn.1674-6899.2018.01.013

Abstract

Abstract:

Objective

To explore the safety and feasibility of transumbilical single port laparoscopic left lateral hepatectomy for hepatocellular carcinoma.

Methods

Clinical data of 28 patients who underwent laparoscopic left lateral hepatectomy in Sun Yat-sen University Cancer Center(SYSUCC) from Jan. to Sep. 2017 were collected. Database was established and analyzed retrospectively. The quantitative data was expressed as percentage and χ² test; qualitative data was measured as the ±s deviation and t test. Additionally, intraoperative bleeding, operation time, postoperative liver function recovery and hospitalization were compared between single and multiple port laparoscopic hepatectomy, respectively.

Results

6 patients were performed with single port laparoscopic left lateral hepatectomy successfully, no case of conversion to laparotomy or adding incision. There was no clinically significant difference between two groups in terms of intraoperative bleeding, postoperative liver function recovery, and hospitalization (P> 0.05). However, the operation time of single port laparoscopic hepatectomy was longer than the conventional laparoscopic surgery [(143.3 ± 57.2)min vs(93.2 ± 22.8)min, P< 0.05]. There was no case of postoperative infection, peritoneal effusion and leakage or other complications.

Conclusions

Single port laparoscopic left lateral hepatectomy was provided with the similar safety and feasibility as conventional laparoscopic surgery. Whereas, the procedures put forward higher technical requirement to surgeons.

Key words: Hepatocellular carcinoma, Hepatectomy, Laparoscopy, Single port

Yangxun Pan, Jinbin Chen, Jiancong Chen, Zhongguo Zhou, Li Xu, Minshan Chen, Yaojun Zhang. Safety and feasibility of single port laparoscopic hepatectomy for hepatocellular carcinoma: a retrospective study[J]. Chinese Journal of Laparoscopic Surgery(Electronic Edition), 2018, 11(01): 47-50.

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References 21

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组别	例数	年龄(岁， ±s)	性别(例)		体质量指数(kg/m²， ±s)	肝炎[例(%)]	肿瘤直径(cm, ±s)	肝功能分级[例(%)]
组别	例数	年龄(岁， ±s)	男	女	体质量指数(kg/m²， ±s)	肝炎[例(%)]	肿瘤直径(cm, ±s)	A级	B级
单孔腹腔镜组	6	57.3 ± 11.1	6	0	23.2 ± 3.8	6(100.0)	3.8 ± 1.2	6(100.0)	0(0.0)
常规腹腔镜组	22	54.3 ± 8.9	20	2	22.1 ± 2.7	20(90.9)	2.7 ± 1.6	20(90.9)	2(9.1)
t值	?	0.699	<0.000		0.830	<0.000	1.581	<0.000
P值	?	0.491	1.000		0.414	1.000	0.126	1.000

组别	例数	年龄(岁， ±s)	性别(例)		体质量指数(kg/m²， ±s)	肝炎[例(%)]	肿瘤直径(cm, ±s)	肝功能分级[例(%)]
组别	例数	年龄(岁， ±s)	男	女	体质量指数(kg/m²， ±s)	肝炎[例(%)]	肿瘤直径(cm, ±s)	A级	B级
单孔腹腔镜组	6	57.3 ± 11.1	6	0	23.2 ± 3.8	6(100.0)	3.8 ± 1.2	6(100.0)	0(0.0)
常规腹腔镜组	22	54.3 ± 8.9	20	2	22.1 ± 2.7	20(90.9)	2.7 ± 1.6	20(90.9)	2(9.1)
t值	?	0.699	<0.000		0.830	<0.000	1.581	<0.000
P值	?	0.491	1.000		0.414	1.000	0.126	1.000

组别	例数	术中出血量(ml)	手术时间(min)	谷丙转氨酶^a(U/L)	谷草转氨酶^a(U/L)	白蛋白^a(g/L)	总胆红素^a(μmol/L)
单孔腹腔镜组	6	66.7 ± 25.8	143.3 ± 57.2	141.2 ± 46.0	102 ± 51.3	39.4 ± 3.7	15.0 ± 5.2
常规腹腔镜组	22	64.6 ± 39.4	93.2 ± 22.8	111.4 ± 61.5	89.5 ± 45.4	39.9 ± 4.9	14.1 ± 6.4
t值	?	0.124	4.570	1.098	0.625	－0.251	0.328
P值	?	0.902	<0.000	0.282	0.537	0.804	0.746
组别	例数	谷丙转氨酶^b(U/L)	谷草转氨酶^b(U/L)	白蛋白^b(g/L)	总胆红素^b(μmol/L)	住院时间(d)
单孔腹腔镜组	6	83.9 ± 25.8	37.3 ± 11.6	43.5 ± 1.4	31.1 ± 6.9	7.3 ± 1.0
常规腹腔镜组	22	63.7 ± 23.1	36.3 ± 16.6	42.7 ± 4.0	27.1 ± 9.8	8.5 ± 1.9
t值	?	1.857	0.140	0.463	0.928	0.164
P值	?	0.075	0.890	0.647	0.362	0.871

组别	例数	术中出血量(ml)	手术时间(min)	谷丙转氨酶^a(U/L)	谷草转氨酶^a(U/L)	白蛋白^a(g/L)	总胆红素^a(μmol/L)
单孔腹腔镜组	6	66.7 ± 25.8	143.3 ± 57.2	141.2 ± 46.0	102 ± 51.3	39.4 ± 3.7	15.0 ± 5.2
常规腹腔镜组	22	64.6 ± 39.4	93.2 ± 22.8	111.4 ± 61.5	89.5 ± 45.4	39.9 ± 4.9	14.1 ± 6.4
t值	?	0.124	4.570	1.098	0.625	－0.251	0.328
P值	?	0.902	<0.000	0.282	0.537	0.804	0.746
组别	例数	谷丙转氨酶^b(U/L)	谷草转氨酶^b(U/L)	白蛋白^b(g/L)	总胆红素^b(μmol/L)	住院时间(d)
单孔腹腔镜组	6	83.9 ± 25.8	37.3 ± 11.6	43.5 ± 1.4	31.1 ± 6.9	7.3 ± 1.0
常规腹腔镜组	22	63.7 ± 23.1	36.3 ± 16.6	42.7 ± 4.0	27.1 ± 9.8	8.5 ± 1.9
t值	?	1.857	0.140	0.463	0.928	0.164
P值	?	0.075	0.890	0.647	0.362	0.871

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