To summarize the clinical efficacy and advantages of laparoscopic hepatectomy for solitary liver metastases after radical esophageal cancer resection.

A retrospective analysis was performed for a patient with isolated liver metastases in the Department of Hepatobiliary Surgery, The Affiliated Drum Tower Hospital, School of Medicine, Nanjing University, in Feb. 2023. Whose right liver lesion was slowly enlarged during 4 cycles of chemotherapy by DCF (docetaxel, cisplatin and 5-fluorouracil) regimen, and then the anatomical laparoscopic right posterior lobectomy were performed.

The patient successfully underwent laparoscopic anatomical right posterior lobe resection of the liver, with less intraoperative bleeding, no postoperative complications such as infection, bleeding, and biliary fistula, and recovered smoothly. The postoperative pathological examination was consistent with the liver metastasis of esophageal cancer. The patient recovered well 6 months after surgery, no recurrence or progression, and continued systematic chemotherapy in the local hospital for 3 cycles.

The laparoscopic minimally invasive resection of solitary liver metastases after oesophageal cancer resection, combined with systemic chemotherapy, improves prognosis and progression-free survival.