Endoscopic multiple mucosal ligation in gastroesophageal reflux disease

doi:10.3877/cma.j.issn.1674-6899.2021.04.008

Abstract

Abstract:

Objective

To explore safety and efficacy of endoscopic multiple mucosal ligation (EMML) for gastroesophageal reflux disease (GERD).

Methods

In the study 17 patients with GERD received EMML from Jun. 2019 to Dec. 2020. The 24 h esophageal pH-resistance monitoring (DeMeester) scores, GERD-questionnaires (GERD-Q) symptom scores and clinical efficacy before and after operation were compared.

Results

All of patients received EMML successively and none severe complication was observed. DeMeester score, GERD-Q symptom score significantly decreased after surgery.

Conclusions

EMML is a feasible, safe and effective method treatment for gastro-esophageal reflux.

Key words: Endoscopic multiple mucosal ligation, Gastroesophageal reflux disease, Endoscopy

Zhichu Qin, Yongjian Zhou, Yongqing Li, Lihao Wu, Wenrui Xie, Yuqiang Nie. Endoscopic multiple mucosal ligation in gastroesophageal reflux disease[J]. Chinese Journal of Laparoscopic Surgery(Electronic Edition), 2021, 14(04): 231-234.

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URL: https://zhqjwkzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.1674-6899.2021.04.008

https://zhqjwkzz.cma-cmc.com.cn/EN/Y2021/V14/I04/231

Figures/Tables 4

References 18

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时间	例数	GERD-Q评分(分)	DeMeester评分(分)	pH<4时间百分比(%)	反流次数(次)	长反流次数(次)	长反流时间(min)
术前	17	11.05±1.52	118.65±76.46	29.86±25.45	231.26±130.12	15.76±9.96	86.54±98.42
术后3个月	17	1.48±1.22	25.88±19.24	9.85±10.68	72.76±58.82	2.46±2.88	12.54±9.87
术后6个月	17	1.66±1.52	28.56±19.98	10.35±11.22	100.32±81.66	4.24±5.64	18.42±16.22

时间	例数	GERD-Q评分(分)	DeMeester评分(分)	pH<4时间百分比(%)	反流次数(次)	长反流次数(次)	长反流时间(min)
术前	17	11.05±1.52	118.65±76.46	29.86±25.45	231.26±130.12	15.76±9.96	86.54±98.42
术后3个月	17	1.48±1.22	25.88±19.24	9.85±10.68	72.76±58.82	2.46±2.88	12.54±9.87
术后6个月	17	1.66±1.52	28.56±19.98	10.35±11.22	100.32±81.66	4.24±5.64	18.42±16.22

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