The argon plasma coagulation in the treatment of tracheal adenoid cystic carcinoma: a clinical study of 19 cases

doi:10.3877/cma.j.issn.1674-6899.2018.04.010

Abstract

Abstract:

Objective

To evaluate the clinical application value of argon plasma coagulation (APC) via bronchoscope in the treatment of tracheal adenoid cystic carcinoma.

Methods

From Jan. 2000 to Dec. 2017 the Chinese PLA General Hospital Department of Respiratory Medicine treated 19 patients with primary adenoid cystic carcinoma of trachea and bronchus were treated with APC via bronchoscope, including 12 cases of adenoid cystic carcinoma of trachea, 7 cases of adenoid cystic carcinoma of bronchus, and all of them treated by argon plasma coagulation (APC) via bronchoscope.

Results

19 patients were followed up for 6-132 months (mean 58.11 months) and the recent effective rate was 100%, cough, chest tightness, shortness of breath and other symptoms improved significantly.And full effectiveness was achieved in 10 cases (53%), partial in 5 cases (26%), mild in 4 cases (21%). The borg index of this 19 patients was declined from(3.5 ± 0.5)to(1.5 ± 0.6)after treatment, the difference was statistically significant (t=6.2, P<0.05)and no serious complications was occured.

Conclusions

APC via bronchoscope is an effective and safe method to treat endobronchial lesions which could resection of tumor effective , keep the airways open, improve the clinical symptoms rapidly, and provide a new treatment option for adenoid cystic carcinoma of trachea and bronchus.

Key words: Trachea and bronchus, Adenoid cystic carcinoma, Bronchoscope, Argon plasma coagulation

Qiang Zhu, Yan Yue, Licheng Zhu, Zhixin Liang, Liangan Chen, Zhen Yang. The argon plasma coagulation in the treatment of tracheal adenoid cystic carcinoma: a clinical study of 19 cases[J]. Chinese Journal of Laparoscopic Surgery(Electronic Edition), 2018, 11(04): 228-233.

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References 20

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序号	年龄	性别	吸烟史	病灶部位	病灶大小(cm)	气道狭窄	转移情况	APC治疗(次)	近期疗效	PFS(月)	复发后APC治疗(次)	生存时间(月)
1	33	女	否	左主支气管	1.6×0.9	30%	ab	1	100%	84	?	121^*
2	56	女	否	气管上段	1.4×1.0	30%	acd	1^m	100%	45	?	46^*
3	37	女	否	气管下段	1.5×0.9	20%	N	1^m	100%	?	?	78
4	37	男	是	气管中段	1.2×1.6	50%	N	1	100%	47	2	63
5	38	女	否	右主支气管	1.4×2.1	90%	N	3	100%	85	2	101
6	59	男	否	气管中段	2.6×1.8	90%	N	3^m	100%	?	?	108
7	62	男	是	气管下段	1.4×1.6	60%	N	1^m	100%	?	?	132
8	61	女	否	气管下段	1.2×1.7	60%	ab	1	100%	?	?	39
9	33	男	否	气管下段	2.1×0.8	30%	N	1	100%	?	?	107
10	64	男	否	左主支气管	1.2×0.9	30%	N	1^m	100%	?	?	80
11	37	男	否	气管中段	1.4×2.0	90%	ad	3^m	100%	25	2	28^*
12	40	男	是	气管上段	1.6×0.8	20%	b	1^mn	100%	33	?	34^*
13	70	男	是	右主支气管	1.3×1.8	80%	N	2	100%	?	?	46
14	35	女	否	左主支气管	1.3×0.8	30%	N	1	100%	?	?	26
15	33	男	是	气管下段	1.2×1.6	60%	N	1^m	100%	?	?	26
16	37	男	否	气管下段	1.5×0.7	20%	N	1	100%	?	?	25
17	62	男	是	右主支气管	2.5×1.6	90%	ab	3^m	100%	?	?	20
18	54	女	否	右主支气管	1.2×1.8	80%	N	2^m	100%	?	?	18
19	38	男	否	气管中段	2.6×1.5	90%	a	3^m	100%	?	?	6

序号	年龄	性别	吸烟史	病灶部位	病灶大小(cm)	气道狭窄	转移情况	APC治疗(次)	近期疗效	PFS(月)	复发后APC治疗(次)	生存时间(月)
1	33	女	否	左主支气管	1.6×0.9	30%	ab	1	100%	84	?	121^*
2	56	女	否	气管上段	1.4×1.0	30%	acd	1^m	100%	45	?	46^*
3	37	女	否	气管下段	1.5×0.9	20%	N	1^m	100%	?	?	78
4	37	男	是	气管中段	1.2×1.6	50%	N	1	100%	47	2	63
5	38	女	否	右主支气管	1.4×2.1	90%	N	3	100%	85	2	101
6	59	男	否	气管中段	2.6×1.8	90%	N	3^m	100%	?	?	108
7	62	男	是	气管下段	1.4×1.6	60%	N	1^m	100%	?	?	132
8	61	女	否	气管下段	1.2×1.7	60%	ab	1	100%	?	?	39
9	33	男	否	气管下段	2.1×0.8	30%	N	1	100%	?	?	107
10	64	男	否	左主支气管	1.2×0.9	30%	N	1^m	100%	?	?	80
11	37	男	否	气管中段	1.4×2.0	90%	ad	3^m	100%	25	2	28^*
12	40	男	是	气管上段	1.6×0.8	20%	b	1^mn	100%	33	?	34^*
13	70	男	是	右主支气管	1.3×1.8	80%	N	2	100%	?	?	46
14	35	女	否	左主支气管	1.3×0.8	30%	N	1	100%	?	?	26
15	33	男	是	气管下段	1.2×1.6	60%	N	1^m	100%	?	?	26
16	37	男	否	气管下段	1.5×0.7	20%	N	1	100%	?	?	25
17	62	男	是	右主支气管	2.5×1.6	90%	ab	3^m	100%	?	?	20
18	54	女	否	右主支气管	1.2×1.8	80%	N	2^m	100%	?	?	18
19	38	男	否	气管中段	2.6×1.5	90%	a	3^m	100%	?	?	6

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