| 1 |
Torre LA, Bray F, Siegel RL, et al. Global cancer statistics, 2012[J]. Ca A Cancer Journal for Clinicians, 2015, 65(2):87-108.
|
| 2 |
Chen W, Zheng R, Zeng H, et al.The incidence and mortality of major cancers in China, 2012[J]. Chinese journal of cancer, 2016, 35(1):73-73.
|
| 3 |
Forner A, Llovet JM, Bruix J．Hepatocellular carcinoma[J]. Lancet, 2012, 379(9822):1245-1255.
|
| 4 |
European Association for Study of L, European Organisation for R, Treatment of C．EASL-EORTC clinical practice guidelines: management of hepatocellular carcinoma[J]. European journal of cancer, 2012, 48(5):599-641.
|
| 5 |
Ashworth T．A case of cancer in which cells similar to those in the tumours were seen in the blood after death[J]. Aust Med J, 1869, 14(1):146-149.
|
| 6 |
Yin CQ, Yuan CH, Qu Z, et al. Liquid biopsy of hepatocellular carcinoma: circulating tumor-derived biomarkers[J]. Disease Markers, 2016, 2016: 1-11.
|
| 7 |
Yin LC, Luo ZC, Gao YX, et al.Twist expression in circulating hepatocellular carcinoma cells predicts metastasis and prognoses[J]. Biomed Research International, 2018, 2018: 1-12.
|
| 8 |
Ao Z, Shah SH, Machlin LM, et al.Identification of cancer-associated fibroblasts in circulating blood from patients with metastatic breast cancer[J]．Cancer research, 2015, 75(22):4681-4687.
|
| 9 |
Adams DL, Martin SS, Alpaugh RK, et al.Circulating giant macrophages as a potential biomarker of solid tumors[J]．Proceedings of the National Academy of Sciences of the United States of America, 2014, 111(9):3514-3519.
|
| 10 |
Mong J, Tan MH.Size-based enrichment technologies for non-cancerous tumor-derived cells in blood[J]．Trends in biotechnology, 2018, 36(5):511-522.
|
| 11 |
Alix-Panabieres C, Pantel K．Challenges in circulating tumour cell research[J]．Nature reviews Cancer, 2014, 14(9):623-631.
|
| 12 |
Yu M, Bardia A, Wittner BS, et al.Circulating breast tumor cells exhibit dynamic changes in epithelial and mesenchymal composition[J]. Science, 2013, 339(6119):580-584.
|
| 13 |
Jie L, Xu H, Xiaona Y, et al. Clinical applications of liquid biopsy as prognostic and predictive biomarkers in hepatocellular carcinoma: circulating tumor cells and circulating tumor DNA[J]. Journal of Experimental & Clinical Cancer Research, 2018, 37(1):213-213.
|
| 14 |
Bruix J, Sherman M, American Association for the Study of Liver D．Management of hepatocellular carcinoma: an update[J]. Hepatology, 2011, 53(3):1020-1022.
|
| 15 |
Heimbach JK, Kulik LM, Finn RS, et al.AASLD guidelines for the treatment of hepatocellular carcinoma[J]．Hepatology, 2018, 67(1):358-380.
|
| 16 |
Matsumura M, Niwa Y, Kato N, et al.Detection of alpha-fetoprotein mRNA, an indicator of hematogenous spreading hepatocellular carcinoma, in the circulation: a possible predictor of metastatic hepatocellular carcinoma[J]．Hepatology, 1994, 20(6):1418-1425.
|
| 17 |
Kong SY, Park JW, Kim JO, et al.Alpha-fetoprotein and human telomerase reverse transcriptase mRNA levels in peripheral blood of patients with hepatocellular carcinoma[J]. Journal of cancer research and clinical oncology, 2009, 135(8):1091-1098.
|
| 18 |
Jin J, Niu X, Zou L, et al.AFP mRNA level in enriched circulating tumor cells from hepatocellular carcinoma patient blood samples is a pivotal predictive marker for metastasis[J]. Cancer letters, 2016, 378(1):33-37.
|
| 19 |
Li J, Chen L, Zhang X, et al.Detection of circulating tumor cells in hepatocellular carcinoma using antibodies against asialoglycoprotein receptor, carbamoyl phosphate synthetase 1 and pan-cytokeratin[J]．PloS one, 2014, 9(4):96185-96185.
|
| 20 |
Mou DC, Cai SL, Peng JR, et al.Evaluation of MAGE-1 and MAGE-3 as tumour-specific markers to detect blood dissemination of hepatocellular carcinoma cells[J]. British journal of cancer, 2002, 86(1):110-116.
|
| 21 |
Bahnassy AA, Zekri AR, El-Bastawisy A, et al.Circulating tumor and cancer stem cells in hepatitis c virus-associated liver disease[J]. World journal of gastroenterology, 2014, 20(48):18240-18248.
|
| 22 |
Choi GH, Kim GI, Yoo JE, et al.Increased expression of circulating cancer stem cell markers during the perioperative period predicts early recurrence after curative resection of hepatocellular carcinoma[J]. Annals of surgical oncology, 2015, 22(3):1444-1452.
|
| 23 |
Guo L, Xu D, Lu Y, et al.Detection of circulating tumor cells by reverse transcriptionquantitative polymerase chain reaction and magnetic activated cell sorting in the peripheral blood of patients with hepatocellular carcinoma[J]. Molecular medicine reports, 2017, 16(5):5894-5900.
|
| 24 |
Maida M, Orlando E, Camma C, et al.Staging systems of hepatocellular carcinoma: a review of literature[J]．World journal of gastroenterology, 2014, 20(15):4141-4150.
|
| 25 |
Wang S, Zhang C, Wang G, et al.Aptamer-mediated transparent-biocompatible nanostructured surfaces for hepotocellular circulating tumor cells enrichment[J]. Theranostics, 2016, 6(11):1877-1886.
|
| 26 |
Xu W, Cao L, Chen L, et al.Isolation of circulating tumor cells in patients with hepatocellular carcinoma using a novel cell separation strategy[J]. Clinical Cancer Research, 2011, 17(11):3783-3793.
|
| 27 |
Feng LH, Dong H, Lau WY, et al.Novel microvascular invasion-based prognostic nomograms to predict survival outcomes in patients after R0 resection for hepatocellular carcinoma[J]. Journal of cancer research and clinical oncology, 2017, 143(2):293-303.
|
| 28 |
Du M, Chen L, Zhao J, et al. Microvascular invasion (MVI) is a poorer prognostic predictor for small hepatocellular carcinoma[J]．BMC Cancer, 2014, 14(1):38-38.
|
| 29 |
Manuel Rodr′l guez-Pera′lvarez, PhD, Luong TV, et al.A systematic review of microvascular invasion in hepatocellular carcinoma: diagnostic and prognostic variability[J]．Annals of Surgical Oncology: An Oncology Journal for Surgeons, 2013, 20(1):325-339.
|
| 30 |
Disibio G, French SW.Metastatic patterns of cancers: results from a large autopsy study[J]．Archives of pathology & laboratory medicine, 2008, 132(6):931-939.
|
| 31 |
Guo P, Bin Cai, Ming Lei, et al.Differential arrest and adhesion of tumor cells and microbeads in the microvasculature[J]. Biomechanics & Modeling in Mechanobiology, 2014, 13(3):537-550.
|
| 32 |
Azevedo AS, Follain G, Patthabhiraman S, et al.Metastasis of circulating tumor cells: favorable soil or suitable biomechanics, or both[J]. Cell Adhesion & Migration, 2015, 9(5):345-356.
|
| 33 |
Chen J, Cao SW, Cai Z, et al.Epithelial-mesenchymal transition phenotypes of circulating tumor cells correlate with the clinical stages and cancer metastasis in hepatocellular carcinoma patients[J]. Cancer biomarkers：section A of Disease markers, 2017, 20(4):487-498.
|
| 34 |
Sun YF, Xu Y, Yang XR, et al.Circulating stem cell-like epithelial cell adhesion molecule-positive tumor cells indicate poor prognosis of hepatocellular carcinoma after curative resection[J]. Hepatology, 2013, 57(4):1458-1468.
|
| 35 |
Felden JV, Schulze K, Krech T, et al.Circulating tumor cells as liquid biomarker for high HCC recurrence risk after curative liver resection[J]. Oncotarget, 2017, 8(52):89978-89987.
|
| 36 |
Li J, Shi L, Zhang X, et al.pERK/pAkt phenotyping in circulating tumor cells as a biomarker for sorafenib efficacy in patients with advanced hepatocellular carcinoma[J]. Oncotarget, 2016, 7(3):2646-2659.
|
| 37 |
Miller MC, Doyle GV, Terstappen LWMM.Significance of circulating tumor cells detected by the cellsearch system in patients with metastatic breast colorectal and prostate cancer[J]. Journal of Oncology, 2010, 2010(1): 617421.
|
| 38 |
Low WS, Wan AW. Benchtop technologies for circulating tumor cells separation based on biophysical properties[J]. Biomed Research International, 2015, 2015(8):1-22.
|
| 39 |
Zheng L, Zou K, Yang C, et al.Inflammation-based indexes and clinicopathologic features are strong predictive values of preoperative circulating tumor cell detection in gastric cancer patients[J]. Clinical and Translational Oncology, 2017, 19(9):1125-1132.
|
| 40 |
Hvichia GE, Parveen Z, Wagner C, et al. A novel microfluidic platform for size and deformability based separation and the subsequent molecular characterization of viable circulating tumor cells[J]. International Journal of Cancer, 2016, 138(12):2894-2904.
|
| 41 |
Lee Y, Guan G, Bhagat AA, et al. A label-free microfluidics technology for enrichment of viable circulating tumor cells[J]. Cytometry Part A：the journal of the International Society for Analytical Cytology, 2018, 93(12):1251-1254.
|
| 42 |
Hou HW, Warkiani ME, Khoo BL, et al.Isolation and retrieval of circulating tumor cells using centrifugal forces[J]．Scientific reports, 2013, 3(7):1259.
|
| 43 |
Pantel K, Alix-Panabieres C．Real-time liquid biopsy in cancer patients: fact or fiction[J]．Cancer Research, 2013, 73(21):6384-6388.
|
| 44 |
Liu Y, Qian J, Feng JG, et al.Detection of circulating tumor cells in peripheral blood of colorectal cancer patients without distant organ metastases[J]．Cellular Oncology, 2013, 36(1):43-53.
|
| 45 |
Lin PP. Integrated EpCAM-independent subtraction enrichment and iFISH strategies to detect and classify disseminated and circulating tumors cells[J]．Clinical and Translational Medicine, 2016, 5(1): 6.
|