切换至 "中华医学电子期刊资源库"

中华腔镜外科杂志(电子版) ›› 2016, Vol. 09 ›› Issue (01) : 15 -18. doi: 10.3877/cma.j.issn.1674-6899.2016.01.005

所属专题: 文献

论著

腹腔镜治疗绝经期卵巢子宫内膜异位囊肿临床分析
王楠1, 范文生1, 顾成磊1, 赵路阳1, 张哲1, 孟元光1,()   
  1. 1. 100853 北京,解放军总医院妇产科
  • 收稿日期:2015-12-18 出版日期:2016-02-28
  • 通信作者: 孟元光
  • 基金资助:
    国家自然科学基金(81272867)

Laparoscopic management of postmenopausal ovarian endometrial cyst

Nan Wang1, Wensheng Fan1, Chenglei Gu1, Luyang Zhao1, Zhe Zhang1, Yuanguang Meng1,()   

  1. 1. Department of Obstetrics and Gynecology, Chinese PLA General Hospital, Beijing 100853, China
  • Received:2015-12-18 Published:2016-02-28
  • Corresponding author: Yuanguang Meng
  • About author:
    Corresponding author: Meng Yuanguang, Email:
引用本文:

王楠, 范文生, 顾成磊, 赵路阳, 张哲, 孟元光. 腹腔镜治疗绝经期卵巢子宫内膜异位囊肿临床分析[J/OL]. 中华腔镜外科杂志(电子版), 2016, 09(01): 15-18.

Nan Wang, Wensheng Fan, Chenglei Gu, Luyang Zhao, Zhe Zhang, Yuanguang Meng. Laparoscopic management of postmenopausal ovarian endometrial cyst[J/OL]. Chinese Journal of Laparoscopic Surgery(Electronic Edition), 2016, 09(01): 15-18.

目的

评价腹腔镜手术治疗绝经期卵巢子宫内膜异位囊肿的安全性和有效性。

方法

回顾性分析2010年6月至2015年6月期间解放军总医院妇产科诊治并经腹腔镜手术病理证实的31例绝经后卵巢子宫内膜异位囊肿患者的临床资料。

结果

患者年龄平均(55.39 ± 5.81)岁,距离绝经时间平均(5.67 ± 5.32)年(95% CI 3.56~7.77)。4例既往有子宫内膜异位症(EMs)病史,其中3例行手术治疗。该病临床症状多不典型,就诊主诉包括发现盆腔包块29例,腹痛6例,绝经后阴道流血1例。结合妇科检查、肿瘤标志物、超声等检查可诊断。患者均行手术治疗,术中r-AFs分期:Ⅰ~Ⅱ期11例,Ⅲ~Ⅳ期20例。术后病理证实合并卵巢肿瘤7例(其中卵巢癌3例),合并子宫腺肌症3例,合并子宫肌瘤5例。其中有26例患者得到随访,未见复发者。

结论

绝经期卵巢EMs患者的病灶很可能在绝经前已存在,临床表现不典型,易于漏诊;根治性手术是诊断及治疗的主要方法。

Objective

To evaluate the effectiveness and safety of postmenopausal ovarian endometrial cyst.

Methods

From Jun. 2010 to Jun. 2015, there were 31 patients of postmenopausal ovarian endometriosis treated with laparoscopic surgery in our hospital. Clinical data were analyzed retrospectively.

Results

The average age was (55.39 ± 5.81) years old. The average period of menopause was (5.67 ± 5.32) years(95% CI 3.56-7.77).4 patients had the history of EMs, with 3 patients had received surgery. Chief complaint included 29 cases of pelvic mass, 6 cases of chronic pelvic pain, 1 case of postmenopausal vaginal bleeding. Endometriosis were preoperatively considered in 16 cases. All patients underwent radical surgery. Stages of r-AFS were 11 cases of stage Ⅰ and Ⅱ, 20 cases of stage Ⅲ and Ⅳ. The final pathologic findings of 31 cases were endometriosis with leiomyoma in 3 cases, adenomyosis in 5 cases, benign ovarian tumor in 4 cases and ovarian cancer in 3 cases.

Conclusions

Postmenopausal ovarian endometriosis was most likely the persistence of premenopausal endometriosis. Because its clinical picture was atypical, it was often misdiagnosed. The radical surgery was the critical methods for diagnosis and treatment.

1
Dietmar H, Radek C, BjRn R, et al. Endometriosis: a premenopausal disease age pattern in 42 079 patients with endometriosis[J]. Archives of Gynecology & Obstetrics, 2012, 286(3): 667-670.
2
Inceboz U. Endometriosis after menopause[J]. Women S Health, 2015, 11(5): 711-715.
3
Wang W, Li R, Fang T, et al. Endometriosis fertility index score maybe more accurate for predicting the outcomes of in vitro fertilisation than r-afs classification in women with endometriosis[J].Reproductive Biology & Endocrinology, 2013, 11(1): 1-10.
4
顾成磊,张唯一,赵路阳,等. 腹腔镜治疗输尿管子宫内膜异位症的临床分析[J/CD]. 中华腔镜外科杂志:电子版,2015,8(3): 10-13.
5
Chen LC, Hsu JW, Huang KL, et al. Risk of developing major depression and anxiety disorders among women with endometriosis: A longitudinal follow-up study[J].Journal of Affective Disorders, 2015, 190(1): 282-285.
6
Kodaman PH. Current strategies for endometriosis management[J]. Obstetrics & Gynecology Clinics of North America, 2015, 42(1): 87-101.
7
陈韦君,周静,梁笑倾. 子宫内膜异位症术后GnRH-α反向添加疗法的效果及其对性激素、骨密度的影响[J].中国妇幼保健,2015,30(4): 513-516.
8
Caruso S, Iraci M, Cianci S, et al. Quality of life and sexual function of women affected by endometriosis-associated pelvic pain when treated with dienogest[J].Journal of Endocrinological Investigation, 2015, 38(11): 1-8.
9
Jeon DS, Kim TH, Lee HH, et al. Endometriosis in a postmenopausal woman on hormonal replacement therapy[J]. Journal of Menopausal Medicine, 2013, 19(3): 151-153.
10
Duru S. Postmenopausal endometriosis: an enigma revisited[J]. J Midlife Health, 2014, 5(4): 163-164.
11
Duru S. Postmenopausal endometriosis - a new dimension[J]. Climacteric the Journal of the International Menopause Society, 2012, 15(5): 507-508.
12
Sun PR, Leng JH, Jia SZ, et al. Postmenopausal endometriosis: a retrospective analysis of 69 patients during a 20-year period[J]. Chinese Medical Journal, 2013, 126(23): 4588-4589.
13
Shen A, Xu S, Ma Y, et al. Diagnostic value of serum CA125, CA19-9 and CA15-3 in endometriosis: a meta-analysis[J]. Journal of International Medical Research, 2015, 43(5): 43.
14
Xiu-Jie Y, Lin Z, Zai-Ping L, et al. Ovarian malignant mixed germ cell tumor with clear cell carcinoma in a postmenopausal woman[J]. International Journal of Clinical & Experimental Pathology, 2014, 7(12): 8996-9001.
15
Garrett LA, Growdon WB, Annekathryn G, et al. Endometriosis-associated ovarian malignancy: a retrospective analysis of presentation, treatment, and outcome[J]. Journal of Reproductive Medicine, 2013, 58(11): 469-476.
16
Burghaus S, Häberle L, Schrauder MG, et al. Endometriosis as a risk factor for ovarian or endometrial cancer-results of a hospital based case control study[J]. Geburtshilfe Und Frauenheilkunde, 2014, 74(1): 1-8.
17
Lee AW, Templeman C, Stram DA, et al. Evidence of a genetic link between endometriosis and ovarian cancer[J]. Fertility & Sterility, 2016, 105(1): 35-43.
18
Li Q, Liu S, Liu H, et al. Significance and implication on changes of serum squamous cell carcinoma antigen in the diagnosis of recurrence squamous cell carcinoma of cervix[J]. Zhonghua Fu Chan Ke Za Zhi, 2015, 50(2): 131-136.
19
Jiming Chen, Hongyan Gao, Qin Li, et al. Efficacy and safety of remifemin on peri-menopausal symptoms induced by post-operative GnRH-a therapy for endometriosis: a randomized study versus tibolone[J]. Medical Science Monitor International Medical Journal of Experimental & Clinical Research, 2014, 20(20): 1950-1957.
[1] 王亚红, 蔡胜, 葛志通, 杨筱, 李建初. 颅骨骨膜窦的超声表现一例[J/OL]. 中华医学超声杂志(电子版), 2024, 21(11): 1089-1091.
[2] 史学兵, 谢迎东, 谢霓, 徐超丽, 杨斌, 孙帼. 声辐射力弹性成像对不可切除肝细胞癌门静脉癌栓患者放射治疗效果的评价[J/OL]. 中华医学超声杂志(电子版), 2024, 21(08): 778-784.
[3] 曹琮沅, 黄烁金, 何倩婷, 王安训. 平阳霉素复合剂治疗口腔颌面部脉管畸形的有效性和安全性[J/OL]. 中华口腔医学研究杂志(电子版), 2024, 18(06): 368-374.
[4] 李华志, 曹广, 刘殿刚, 张雅静. 不同入路下行肝切除术治疗原发性肝细胞癌的临床对比[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 52-55.
[5] 陈浩, 王萌. 胃印戒细胞癌的临床病理特征及治疗选择的研究进展[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 108-111.
[6] 屈翔宇, 张懿刚, 李浩令, 邱天, 谈燚. USP24及其共表达肿瘤代谢基因在肝细胞癌中的诊断和预后预测作用[J/OL]. 中华普外科手术学杂志(电子版), 2024, 18(06): 659-662.
[7] 许月芳, 刘旺, 曾妙甜, 郭宇姝. 多粘菌素B和多粘菌素E治疗外科多重耐药菌感染临床疗效及安全性分析[J/OL]. 中华普外科手术学杂志(电子版), 2024, 18(06): 700-703.
[8] 刘柏隆, 周祥福. 压力性尿失禁阶梯治疗的项目介绍[J/OL]. 中华腔镜泌尿外科杂志(电子版), 2025, 19(01): 125-125.
[9] 刘柏隆. 女性压力性尿失禁阶梯治疗之手术治疗方案选择[J/OL]. 中华腔镜泌尿外科杂志(电子版), 2025, 19(01): 126-126.
[10] 李浩, 陈棋帅, 费发珠, 张宁伟, 李元东, 王硕晨, 任宾. 慢性肝病肝纤维化无创诊断的研究进展[J/OL]. 中华临床医师杂志(电子版), 2024, 18(09): 863-867.
[11] 谭瑞义. 小细胞骨肉瘤诊断及治疗研究现状与进展[J/OL]. 中华临床医师杂志(电子版), 2024, 18(08): 781-784.
[12] 王誉英, 刘世伟, 王睿, 曾娅玲, 涂禧慧, 张蒲蓉. 老年乳腺癌新辅助治疗病理完全缓解的预测因素分析[J/OL]. 中华临床医师杂志(电子版), 2024, 18(07): 641-646.
[13] 王子阳, 王宏宾, 刘晓旌. 血清标志物对甲胎蛋白阴性肝细胞癌诊断的研究进展[J/OL]. 中华临床医师杂志(电子版), 2024, 18(07): 677-681.
[14] 陈慧, 邹祖鹏, 周田田, 张艺丹, 张海萍. 皮肤镜对头皮红斑性皮肤病辅助鉴别诊断的研究进展[J/OL]. 中华临床医师杂志(电子版), 2024, 18(07): 692-698.
[15] 崔军威, 蔡华丽, 胡艺冰, 胡慧. 亚甲蓝联合金属定位夹及定位钩针标记在乳腺癌辅助化疗后评估腋窝转移淋巴结的临床应用价值探究[J/OL]. 中华临床医师杂志(电子版), 2024, 18(07): 625-632.
阅读次数
全文


摘要


AI


AI小编
你好!我是《中华医学电子期刊资源库》AI小编,有什么可以帮您的吗?