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中华腔镜外科杂志(电子版) ›› 2018, Vol. 11 ›› Issue (04) : 228 -233. doi: 10.3877/cma.j.issn.1674-6899.2018.04.010

所属专题: 经典病例 文献

论著

氩等离子体凝固术治疗气管腺样囊性癌19例效果分析
朱强1, 岳岩1, 朱立成2, 梁志欣1, 陈良安1, 杨震1,()   
  1. 1. 100853 北京,解放军总医院呼吸科
    2. 226000 南通,江苏省南通市第三人民医院呼吸科
  • 收稿日期:2018-01-24 出版日期:2018-08-30
  • 通信作者: 杨震

The argon plasma coagulation in the treatment of tracheal adenoid cystic carcinoma: a clinical study of 19 cases

Qiang Zhu1, Yan Yue1, Licheng Zhu2, Zhixin Liang1, Liangan Chen1, Zhen Yang1,()   

  1. 1. Department of Pneumology, General Hospital of PLA, Beijing 100853, China
    2. Department of Pneumology, The Third People′s Hospital of Nantong in Jiangsu Province, Nantong 226000, China
  • Received:2018-01-24 Published:2018-08-30
  • Corresponding author: Zhen Yang
  • About author:
    Corresponding author: Yang Zhen, Email:
引用本文:

朱强, 岳岩, 朱立成, 梁志欣, 陈良安, 杨震. 氩等离子体凝固术治疗气管腺样囊性癌19例效果分析[J/OL]. 中华腔镜外科杂志(电子版), 2018, 11(04): 228-233.

Qiang Zhu, Yan Yue, Licheng Zhu, Zhixin Liang, Liangan Chen, Zhen Yang. The argon plasma coagulation in the treatment of tracheal adenoid cystic carcinoma: a clinical study of 19 cases[J/OL]. Chinese Journal of Laparoscopic Surgery(Electronic Edition), 2018, 11(04): 228-233.

目的

评价经支气管镜氩等离子体凝固术(argon plasma coagulation, APC)在气管支气管腺样囊性癌治疗中的临床应用价值。

方法

回顾性分析2000年1月至2017年12月解放军总医院呼吸科收治的原发性气管支气管腺样囊性癌患者19例,其中12例气管腺样囊性癌、7例支气管腺样囊性癌,均行经支气管镜氩等离子体凝固术治疗。

结果

19例患者进行了6~132个月(平均58.11个月)的随访,定期行胸部CT和支气管镜检查,治疗后近期有效率为100%,咳嗽、胸闷、气短等症状明显改善。其中完全有效10例(53%)、部分有效5例(26%)、轻度有效4例(21%)。19例患者气促指数,治疗前(3.5± 0.5)级、治疗后(1.5±0.6)级,差异有统计学意义(t=6.2,P<0.05)。无严重并发症。

结论

APC对于气道腔内病变的治疗安全有效,可有效切除肿瘤,保证气道通畅,迅速改善临床症状,为气管支气管腺样囊性癌提供一种新的治疗选择。

Objective

To evaluate the clinical application value of argon plasma coagulation (APC) via bronchoscope in the treatment of tracheal adenoid cystic carcinoma.

Methods

From Jan. 2000 to Dec. 2017 the Chinese PLA General Hospital Department of Respiratory Medicine treated 19 patients with primary adenoid cystic carcinoma of trachea and bronchus were treated with APC via bronchoscope, including 12 cases of adenoid cystic carcinoma of trachea, 7 cases of adenoid cystic carcinoma of bronchus, and all of them treated by argon plasma coagulation (APC) via bronchoscope.

Results

19 patients were followed up for 6-132 months (mean 58.11 months) and the recent effective rate was 100%, cough, chest tightness, shortness of breath and other symptoms improved significantly.And full effectiveness was achieved in 10 cases (53%), partial in 5 cases (26%), mild in 4 cases (21%). The borg index of this 19 patients was declined from(3.5 ± 0.5)to(1.5 ± 0.6)after treatment, the difference was statistically significant (t=6.2, P<0.05)and no serious complications was occured.

Conclusions

APC via bronchoscope is an effective and safe method to treat endobronchial lesions which could resection of tumor effective , keep the airways open, improve the clinical symptoms rapidly, and provide a new treatment option for adenoid cystic carcinoma of trachea and bronchus.

图1 术前肺CT肺窗
图2 术前肺CT纵隔窗
表1 原发性气管支气管腺样囊性癌患者19例的临床资料比较
图3 术前气管镜下表现
图4 术后气管镜下表现
图5 无疾病进展生存期、总生存期变化情况
1
Yu X, Zhu H, Xu T. Diagnosis of cylindroma in emergency department[J]. China Journal of Modern Medicine, 2002,12(5):54-55.
2
Udaya BS.Advances in bronchoscopic procedures[J].Chest,1999,116(1):1403-1408.
3
Gagner M.Endoscopoic subtotal parathytoroidectomy in patients with primary hyperparathyroidism[J].Br J Surg,1996,83(6):875-877.
4
Ohagmin M, Ishil S, Arosawa Y,et al.Scarless endoescopic thy-roidectomy:brest approach for better cosmesis[J].Surg Laparosc Endosc Percutan Tech,2000,10(1):1-4.
5
Cleveland RH, Jr NC, Ziskind J. Primary adenoid cystic carcinoma (cylindroma) of the trachea[J]. Radiology, 1977, 122(3):597-600.
6
赵宏光,许顺,张林,等. 外科诊治原发性气管腺样囊性癌11例[J]. 中华结核和呼吸杂志, 2003, 26(7):400-402.
7
Maziak DE, Todd TR, Keshavjee SH, et al. Adenoid cystic carcinoma of the airway: thirty-two-year experience[J]. J Thorac Cardiovasc Surg, 1996, 112(6):1522-1532.
8
Grillo HC, Mathisen J. Primary tracheal tumors: treatment and results[J]. Annals of Thoracic Surgery, 1990, 49(1):69-77.
9
Regnard JF, Fourquier P, Levasseur P. Results and prognostic factors in resections of primary tracheal tumors: a multicenter ret-respective study.the french society of cardiovascular surgery[J]. Journal of Thoracic & Cardiovascular Surgery, 1996, 111(4):808-814.
10
Spiro RH, Huvos AG, Strong EW. Adenoid cystic carcinoma: factors influencing survival[J]. American Journal of Surgery, 1979, 138(4):579-583.
11
李强. 呼吸内镜学[M].上海:上海科学技术出版社,2003:214-223.
12
王洪武.电子支气管镜的临床应用[M].北京:中国医药科技出版社,2009:188-212.
13
Reichle G, Freitag L, Kullmann HJ, et al. Argon plasma coagulation in bronchology: a new method--alternative or complementary[J]. Journal of Bronchology, 2000, 7(11):508-516.
14
Maziak DE, Todd TR, Keshavjee SH, et al. Adenoid cystic carcinoma of the airway: thirty-two-year experience[J]. J Thorac Cardiovasc Surg, 1996, 112(6):1522-1532.
15
Gaissert HA, Grillo HC, Shadmehr MB, et al. Long-term survival after resection of primary adenoid cystic and squamous cell carcinoma of the trachea and carina[J]. Annals of Thoracic Surgery, 2004, 78(6):1889-1896.
16
Shimizu J, Oda M, Matsumoto I, et al. Clinicopathological study of surgically treated cases of tracheobronchial adenoid cystic carcinoma[J]. General Thoracic & Cardiovascular Surgery, 2010, 58(2):82-86.
17
Sasiaja M, Funa N, Kamata M, et al. Unresectable adenoid cystic carcinoma of the trachea treated with chemoradiotherapy[J]. Clinical Oncology, 2000, 12(4):272-272.
18
王永岗,张宏图. 气管、支气管腺样囊性癌[J]. 中华胸心血管外科杂志, 2000, 16(6):357-358.
19
Sutedja G, Bolliger CT. Endobronchial electrocautery and argon plasma coagulation[J]. Interventional Bronchoscopy Progress in Respiratory Research, 2004, 30(1):120-132.
20
杨震,姜丹丹,田庆,等.支气管镜介入治疗顽固性气胸的进展[J/CD]].中华腔镜外科杂志(电子版),2014,7(4):60-63.
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